At the age of 43

• 02-October-1535 : Jacques Cartier reaches the area (island) in the St. Lawrence River that eventually becomes Montreal, Quebec.
• 19-May-1535 : French explorer Jacques Cartier sets sail for his second voyage to North America with 3 ships, 110 men, and Chief Donnacona's 2 sons (who Cartier took during his first voyage).
• 01-June-1533 : King Henry VIII of England's marriage with Catherine of Aragon is officially declared annulled by Archbishop Thomas Cranmer. However, since Pope Clement VII had already rejected Henry's petition for annulment in 1530, Catherine continues to believe herself Henry's wife until her death. Thomas Cranmer crowns Anne Boleyn, wife of Henry VIII of England, in Westminster Abbey as queen. Pope Clement VII responds to the marriage by excommunicating both Henry and Cranmer from the Roman Catholic Church.
• 30-March-1533 : Although secretly married to the niece of Lutheran scholar Andreas Osiander, Margaret, in violation of his vow of celibacy, Thomas Cranmer becomes Archbishop of Canterbury.
• 21-April-1526 : First battle of Panipat: Babur becomes Moghul (or Mughal) emperor of India, captures Delhi, and invades northern India, beginning the Mughal Empire, which lasts until 1857.
• 11-August-1259 : While conducting a siege against the Song Dynasty city known as Fishing Town in the province of Chongqing, China, the Mongol Khagan, Mongke Khan, dies in the nearby hills. Persian, Chinese, and Mongol records have different accounts of how he died, including succumbing to an arrow wound received by a Chinese archer in the siege, dysentery, and even a cholera epidemic. His death sparks a succession crisis in the Mongol Empire, while his brothers Ariq Boke and Kublai soon convene their own kuriltai to elect themselves as the next Khan of Khans, opening the path to a 44 yearyearlong civil war from 1260 to 1264. In the end, Ariq Boke surrenders to Kublai.
• 03-June-1162 : Thomas Becket is consecrated as Archbishop of Canterbury.
• 22-August-0565 : St. Columba reports seeing a monster in Loch Ness, Scotland.